NOT KNOWN FACTUAL STATEMENTS ABOUT PKRRATING

autophosphorylation at T466 isn't feasible In this particular geometry as well as docking web site on helix αG for your substrate eIF2α is blocked. However, similar interfaces utilizing the αEF and αG helices have already been reported for trans-autophosphorylation complexes of PAK159 and PknB60. The mechanistic relevance of activation loop ex